Beilstein J. Org. Chem.2014,10, 1741–1748, doi:10.3762/bjoc.10.181
by the preparation of a second vaccine candidate which incorporated an additional promiscuous T-helper epitope.
Keywords: amino acid lipidation; cycloadditon reaction; multivalent glycosystems; peptidevaccine; tetrapropargyl glucopyranose; Introduction
Vaccination is often the most effective and
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Graphical Abstract
Scheme 1:
Convergent construction of self-adjuvanting vaccines bearing multiple copies of a B cell epitope.